The museum was established due to donations. The building was donated in 1971, and the furniture, books, documents, and decorations in 1974 by Florica Magheru, a relative of Petru Poni's. Other donations were made by family descendants or students of these personalities: Professor Elena Bogdan, daughter of Petru Bogdan, Eng. Octav Gheorghiu, Ph.D., C.V. Gheorghiu's son, Professor Nicolae Asandei's family, eng. Vasile Pintiuc, Professor Vasile Ababei, the researcher Gh. Stoica, and others. The museum was organized by a team from the Jassy Polytechnic Museum. The building is a historic monument built in 1838 by Veniamin Costache (1768 - 1846). The house became the property of Petru Poni in 188...0. In 1971 Margareta Poni, the scholar's daughter, following a request met by the country's government, donated to the Jassy Museum Complex - through the Jassy City Council - the house that belonged to Petru Poni. The museum collection includes memorial artefacts relating to the life and activity of the chemist scholar Petru Poni (1841 - 1925), one of the founders of Romanian mineralogy, and those of other researchers in the field of chemistry like the academician Radu Cernătescu, Petru Bogdan, Nicolae Costăchescu, Anastasie Obregia, C. V. Gheorghiu, Ilie Matei, Gheorghe Alexa, Mihai Dima, and Ion Zugrăvescu; documents, photographs, devices, and samples; pieces of furniture from the second half of the 19th century; decorations; the first Romanian college books for chemistry and physics worked out by Petru Poni and issued in 1869 and 1874, rare books, collections of scientific reviews, scientific diplomas. Three memorial rooms are dedicated to Petru Poni: the reception room, the sitting room (dedicated to the poetess Matilda Cugler-Poni) and the library. Another memorial room is dedicated to Radu Cernătescu. In other two rooms are presented the Jassy personalities in the field of chemistry, as well as instances from the fields of education, research, design and industry in Jassy.